Author Archives: Kayla Barnes

Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054

Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Learn more about Bérénice Benayoun:LinkedIn: https://www.linkedin.com/in/b%C3%A9r%C3%A9nice-benayoun-a374a74b/en/Website: https://gero.usc.edu/labs/benayounlab/Her New Study (Estropausal gut microbiota transplant improves measures of ovarian function in adult mice): https://pubmed.ncbi.nlm.nih.gov/41776310/

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain Biohacking with Kayla Barnes — Dr. Deb Rivera, PhD: The Missing Link Between Stress, Aging, and Resilience

April 2, 2026

Most people can feel when stress is affecting them. Far fewer know whether their body is adapting well or quietly being pushed toward dysfunction.

In this episode, Dr. Deb Rivera, PhD in neuroengineering, explains the hidden biological system that helps determine how well your body handles stress. Her research focuses on redox balance and the glutathione ratio, a biomarker that may reveal whether your body is adapting to stress or slowly moving toward dysfunction.

In This Conversation

-How to tell whether stress is helping or harming the body-The glutathione ratio and what it reveals about resilience-The role of redox balance in aging and metabolic health-Why recovery capacity determines how you respond to stress-How lifestyle factors influence mitochondrial and cellular health-Microplastics, environmental stressors, and biological resilience-Practical ways to support your body’s stress-adaptation system

Connect with Kayla:

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Learn more about Dr. Deb Rivera:

LinkedIn: https://www.linkedin.com/in/journeymetrics/

Website: https://journeymetrics.io/

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain Biohacking with Kayla Barnes — Dr. Eboni Cornish, MD: Brain Longevity, Neuroinflammation, and What Quietly Damages the Brain

March 26, 2026

Brain health problems rarely begin where most people look. Memory issues, low mood, poor focus, anxiety, and even early cognitive decline can be driven by hidden inflammation and root-cause imbalances long before they show up the way most people expect.

In this episode, Dr. Eboni Cornish explains how chronic infections, mold, toxins, hormones, gut dysfunction, and oral or nasal microbial imbalances can all affect the brain, and why “mental health” often needs to be approached as brain health first.

She also shares how tools like brain imaging, inflammation markers, and functional testing can uncover patterns that are often missed in standard workups, while outlining the core foundations that support long-term brain health, including sleep, exercise, omega-3s, vitamin D, hormone balance, gut health, and detox capacity.

In This Conversation:

– Why brain symptoms can start outside the brain

– How neuroinflammation can affect mood, focus, and memory

– Mold, Lyme, Epstein

-Barr, and other overlooked brain disruptors

– Why gut, oral, and nasal health matter for cognition

– The tests and markers that can reveal early brain stress

– The foundations that support brain longevity

Connect with Kayla:

YouTube: http://www.youtube.com/@KaylaBarnesLentz

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Learn more about Eboni Cornish:

Instagram: https://www.instagram.com/dr.ebonicornish/

TikTok: https://www.tiktok.com/@drebonicornish

Website: https://www.drebonicornish.com/

Amen Clinics: https://www.amenclinics.com/team/eboni-cornish-md/

Brain Biohacking with Kayla Barnes — Jessie Inchauspé Glucose Goddess on CGMs, Crashes & The Biggest Glucose Mistakes

March 19, 2026

Blood sugar stability may be one of the most important levers for long term health, yet most people never look at it.In this episode, I am joined by Jessie Inchauspé, widely known as the Glucose Goddess, to examine what glucose spikes are actually doing inside the body and why they matter even if you are not diabetic.We unpack how glucose spikes can influence your mood, focus, cravings, and energy levels, why blood sugar stability matters even if you are not diabetic, and how seeing your own patterns can completely change the way you approach food.Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/checkout/become-a-memberWe also cover:- The biggest glucose mistakes most people make- Why “healthy” breakfasts often lead to energy crashes- How dinner timing impacts deep sleep- The connection between glucose spikes and skin aging through glycation- Simple strategies like food order and walking after meals- How a mother’s glucose levels can influence her baby’s long term metabolic riskUnderstanding your glucose patterns gives you leverage, and small, strategic shifts can compound into measurable long term health improvements.

Connect with Kayla:

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Connect with Glucose Goddess:Website: https://www.glucosegoddess.com/YouTube: https://www.youtube.com/@GlucoseRevolutionInstagram: https://www.instagram.com/glucosegoddess/TikTok: https://www.tiktok.com/@glucosegoddess_Pre-order her new book: https://www.glucosegoddess.com/pages/9-months-that-count-forever

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain Biohacking with Kayla Barnes — Dr. Deanna Minich, PhD: How Women Should Structure Macros in Their Meals

March 12, 2026

Women are told to fast, cut carbs, eat high protein, avoid seed oils, and track macros, but most of that advice ignores female physiology.

In this episode, I’m joined by Dr. Deanna Minich, PhD, certified functional medicine practitioner and nutrition scientist. We walk through the Female Longevity Nutrition Protocol she created, including circadian timing, macro ranges by life stage, and how to stop getting whiplash from internet nutrition trends.

In This Conversation:

The “breakfast myth” and why your ovaries won’t shrink
Eating earlier in the day, circadian timing, and appetite regulation
Macro ranges by life stage and why Deanna uses ranges, not rigid targets
Perimenopause and postmenopause macro shifts
Omega Index testing and why it matters
Fiber, fats, seed oils, and what the research actually supports
Micronutrient testing and how to personalize nutrition and supplements

Connect with Kayla:

Spotify:https://open.spotify.com/show/4OLWWn22…YouTube: http://www.youtube.com/@KaylaBarnesLentz

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Learn more about Dr. Deanna Minich:

Instagram: https://www.instagram.com/deannaminich/

Website: https://deannaminich.com/

YouTube: http://www.youtube.com/@foodandspirit

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain Biohacking with Kayla Barnes — Dr. Susanna Søberg, PhD: The Science of Cold Plunges for Women

March 5, 2026

Cold exposure is not a badge of toughness. It’s a stressor.

And if you do it wrong, you can absolutely overdo it.

In this episode, I’m joined by Dr. Susanna Søberg, PhD, scientist and educator specializing in metabolism, cold and heat exposure, and longevity. We break down what cold exposure is actually doing in the body, why brown fat matters for metabolic health, and how women should think about timing cold exposure around PMS, luteal phase, and menstruation.

In This Conversation:

-Why cold exposure works best when it’s short and strategic

-Brown fat, insulin sensitivity, and why it doesn’t have to be “that cold”

-Cold vs heat for women, and why “better” depends on the outcome

-PMS timing and when to pull back on stressors

-Temperature, time, and the real dose-response of cold exposure

-How to spot viral claims that sound exciting but aren’t science

Connect with Kayla:

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Learn more about Susanna Søberg, PhD:

Instagram: https://www.instagram.com/susanna_soeberg

Website: https://soeberginstitute.com/

Thermalist Women’s Retreat With Dr. Susanna Søberg: https://soeberginstitute.com/pages/thermalist%C2%AE-women-s-retreat

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain Biohacking with Kayla Barnes — Dr. Stephanie Riley Hahn: Pelvic Floor Dysfunction, Leaks, Painful Sex, And Prolapse

February 26, 2026

Pelvic floor problems are not a “just do more kegels” issue.For a lot of women, kegels are either not specific enough, or they make symptoms worse.

In this episode, Dr. Stephanie Riley Hahn, pelvic floor physical therapist and founder of Longevity and Pilates, breaks down what pelvic floor dysfunction actually is, how to tell weakness from tightness, and why pressure management and breathing mechanics often matter more than squeezing harder.

In this conversation:

Why pelvic floor tightness can drive pain, irritation and symptoms
The difference between weakness and tension, and how to tell
How breathing and pressure management change everything
What downtraining involves, and what tends to backfire
Prolapse support options, and when to seek help
Overactive bladder and constipation patterns that keep symptoms alive

Connect with Kayla:

YouTube: http://www.youtube.com/@KaylaBarnesLentz

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Learn more about StephanieInstagram: https://www.instagram.com/longevityptpilates/Website: https://www.longevityptandpilates.com/

Shownotes:Pelvic floor PT locator: https://www.aptapelvichealth.org/ptlocator

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain Biohacking with Kayla Barnes — Dr. Aimie Apigian: The Biology of Trauma, Nervous System Safety and Somatic Healing

February 19, 2026

Longevity isn’t just workouts, supplements, and recovery tools, it starts with nervous system health.

In this episode, Dr. Aimie Apigian explains what trauma actually is (not a label, but a measurable physiological response), how the body shifts from stress into overwhelm, and why “pushing through” often turns into years of avoidance, numbing, and hidden internal strain.

She breaks down the biology behind the trauma response, including the role of adrenaline, cortisol timing, and how mitochondrial capacity influences resilience.

You’ll also learn her practical, body-based approach to creating “safe enough” in real time, plus the three phases of healing: safety, support, and expansion, so you don’t stay stuck avoiding triggers forever.

In this conversation:

Stress vs trauma response (and what changes physiologically)
Why adrenaline drives the response and cortisol arrives later
How the body stores trauma as patterns, not just memories
The 3 nervous system states and the thoughts they generate
A simple somatic exercise to build safety in the body
Why devices/meds can be bridges, not the destination
Using biomarkers + wearables without fooling yourself
Why modern media can create vicarious trauma

Connect with Kayla:

YouTube: http://www.youtube.com/@KaylaBarnesLentz

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Learn more about Dr. Aimie Apigian, MD:

Instagram: https://www.instagram.com/draimie/

YouTube: https://www.youtube.com/c/DrAimieApigian

Website: https://www.biologyoftrauma.com/

Order her Book “The Biology of Trauma”: https://www.biologyoftrauma.com/book

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain Biohacking with Kayla Barnes — I Became the First Woman in the World to Test Her Ovarian Age

February 14, 2026

For the first time in history, ovarian biological age can be measured, and I became the first woman in the world to take the test.

Until now, women have had no real way to understand how their ovaries are aging beyond rough estimates like AMH. But this new machine-learning algorithm, trained on over 40,000 real women across different life stages, analyzes hormone biomarkers, body composition, and reproductive history to estimate ovarian age relative to chronological age.

This is a massive step forward in female longevity science.

In this episode, I walk through what the test measures, how the algorithm works, and what becoming the first data point actually means, not just for me, but for women collectively. We also explore what may be driving ovarian aging in the first place.

I also share how I’m now testing specific interventions in isolation, including hyperbaric oxygen therapy, to determine whether we can meaningfully influence ovarian aging over time.

Ovarian lifespan is significantly shorter than overall lifespan and once we can measure it, we can begin to understand it.

This is only the first step in redefining female longevity.

*Kayla's social + website:*

Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Twitter: https://x.com/femalelongevity

Website: https://www.kaylabarnes.com

Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

SHOW NOTES:

00:01:03 Timeless Biotech Website:https://timelessbiotech.com/

00:01:13 Podcast With The Founder of Timeless Biotech:https://www.youtube.com/watch?v=s-_EuNUwjsM&t=57s

00:04:12 Kayla’s Protocols:https://www.protocol.kaylabarnes.com/

00:09:58 Podcast With Dr. Chris Masterjohn:https://www.youtube.com/watch?v=z3quYW_pCDU

00:10:48 Study About Ovarian Stiffness Increasehttps://pmc.ncbi.nlm.nih.gov/articles/PMC7681059/#acel13259-sec-0002

00:16:22 Study For Increased PFAShttps://pubmed.ncbi.nlm.nih.gov/41620147/

00:17:56 Red Light Therapy Study:

https://www.sciencedirect.com/science/article/abs/pii/S1011134424001842?via=ihub